Doctors at Vatican hospital separate conjoined twins whose skulls were fused

Doctors at Vatican hospital separate conjoined twins whose skulls were fused
Italy Conjoined Twins

Doctors at the Vatican’s paediatric hospital said they have successfully separated conjoined twins whose skulls were fused back-to-back, an exceedingly rare surgery for an equally rare congenital defect.

The twins, Ervina and Prefina Bangalo, were born June 29, 2018 in Mbaiki, Central African Republic with their heads attached and sharing critical blood vessels around their brains.

Such cases of conjoined twins occur once in every two million births or so.

The Bambino Gesu Paediatric Hospital, which is Vatican-owned but operates within the Italian public health system, brought the twins and their mother to Italy soon after their birth.

The hospital said the toddlers are recovering well a month after their third and definitive separation surgery on June 5.

Video released by the hospital showed the girls waving along to music from their beds, clapping and holding markers, as well as celebrating their second birthday in their mother’s arms as hospital staff sang Happy Birthday to them in Italian.

Ermine, mother of conjoined twins Ervina and Prefina (Riccardo de Luca/AP)

The key goal of the surgery was “to obtain a separation with the girls in perfect condition.

So the objective we gave ourselves was very ambitious, and we did everything to reach it,” Dr Carlo Marras, chief of paediatric neurosurgery at Bambino Gesu, said.

Dr Marras led the team that worked for nearly two years planning and executing the separation.

At a press conference to announce the outcome of the sisters’ surgery, Dr Marras said the prognosis was “these girls can have a normal life” after a phase of rehabilitation.

There have been successful separation surgeries in the past of twins joined at the head, but most have been for twins whose heads were fused vertically, at the top.

Ervina and Previna’s skulls were joined back-to-back in what is known as “total posterior craniopagus”.

That made the surgery particularly challenging since the back of the head is a far more critical place for blood supply to the brain and drainage of blood away from it, said Dr Jesse Taylor, head of plastic surgery at the Children’s Hospital of Philadelphia who has participated in some separation surgeries.

It is hoped Pope Francis will baptise the girls (Riccardo De Luca/AP)

“It’s one of those configurations that I think a lot of centres, when they see it, say, ‘You know, we’re not sure that this can be done safely’,” Dr Taylor said.

“The venous drainage tends to be the main limiting step for separability” in twins connected at the back of the head.

He said in typical separation surgeries, doctors can “borrow” some blood vessels to give to each twin.

“But when it comes to the back of the head, you don’t have a lot of wiggle room for borrowing veins,” Dr Taylor explained.

Dr Marras said that indeed, the most complicated aspect of the Bangalo twins’ separation was to give each child autonomous venous drainage systems, procedures that began with two surgeries in May and June 2019.

The final, 18-hour surgery last month to physically separate them involved a team of 30 doctors and nurses, who made use of 3-D imaging and neurosimulators.

Before the separation surgery, members of the Vatican hospital’s staff gave the girls mirrors so they could see one another.

Carlo Efisio Marras, head of the Bambino Gesu’ (Baby Jesus) paediatric hospital neurosurgery department (Riccardo De Luca/AP)

They knew what each other sounded like, but the mirrors helped them associate facial expressions with their personalities and sounds, Dr Marras said.

“It was an experience that wasn’t just professional but above all human: to think that you can arrive at something that we had only imagined, with all the possibilities of failure.

“It was a magical moment. Marvellous,” he said.

Dr Marras said there was only one previously known case of a separation of twins conjoined at the back of the head, performed in the United States during the 1980s.

He said the outcome in that case was poor.

He was referring to the 1987 surgery at Johns Hopkins University by a team led by Dr Ben Carson, who is now US President Donald Trump’s housing secretary.

Both twins suffered serious neurological problems; two years after the surgery, one of the boys was reportedly in a vegetative state and the other had severe developmental delays.

In the case of the sisters from Central African Republic, Dr Marras said the girls so far have suffered no neurological harm.

The twins’ mother, Ermine Nzotto, wiped tears from her eyes as she watched a video prepared by the hospital of the twins’ before and after their separation.

Ms Nzotto said she never went to school but hopes her daughters would study to become doctors.

“It’s a joy, that I can see my girls run and play like other children.

“May they tomorrow study and learn to become doctors to save the other children of this world,” she said through an interpreter.

The mother thanked Dr Marras, the hospital president and Pope Francis, who visited Central African Republic’s capital of Bangui in 2015 and has since strongly supported Bambino Gesu’s collaboration with the paediatric hospital there.

Ms Nzotto said she also hopes that Francis will now baptise her girls.

Hospital President Mariella Enoc had met the twins soon after they were born during a visit to the Central African Republic and was the driving force behind bringing them to Rome and seeing if they could be separated.

She said deciding to do so created ethical and economic questions, since the cost of one million euros (1.1 million US dollars) paid for primarily by the hospital foundation could have been spent on less-risky procedures that might have benefited more children.

But Ms Enoc said: “When you find a life that can be saved, you have to save it.”

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