The Minister for Health Stephen Donnelly is self-isolating after experiencing symptoms of Covid-19.
The Department of Health confirmed a press conference on Budget 2022's health allocation will be postponed until Thursday due to Mr Donnelly's absence.
A statement said the Minister "has experienced mild symptoms of Covid-19".
"As per public health advice, Minister Donnelly immediately self-isolated and arranged a test which has returned a not-detected result," the department added.
Mr Donnelly will continue to work from home until the symptoms subside in accordance with public health advice.