The Youghal native, who previously impressed in the Sevens versions of rugby, was given a start in the out-half berth at Donnybrook as Ireland emerged 31-12 winners.
The Irish had beaten Scotland in a tough test a week earlier but pushed into a 14-point lead at half-time.
The harsh weather didn't help either side but the hosts were able to manage their advantage cleverly in the second half.
Keohane was previously known on Leeside for her GAA excellence, representing Cork teams at various levels in hurling and ladies football.
Last week the 28-year-old explained her sporting background: “For me, I grew up playing rugby underage at home in Youghal. I played with the boys up until I was about 11, my brother was playing in there and I was dragged in too. I was exposed to rugby at a very young age and I absolutely loved it. It’s fantastic that now there are pathways for girls to play right up through their teens and progress into adult rugby.
“That wasn’t there at the time for me, so the natural progression was to play camogie and football. When I went back to college in UL I always had it in the back of my head that I’d love to go back and play rugby again. The skill-sets, from an athleticism point of view, all cross over – particularly Gaelic football into Sevens.
"It’s very much just learning the game, and that’s for me as well coming from predominantly playing Sevens over the last number of years into 15s. Getting comfortable in that position and learning the game, the girls make that easier for you too.”