The former Blacktie premises at the northern end of Patrick's Street is to become Fálte Ireland's new flagship premises in Cork.
The tourism organisation will relocate from their current location on the Grand Parade. Failte Ireland sold the current building on Grand Parade in November.
It is not yet known who will takeover the premises once Fáílte Ireland vacate it.
The tourism body said they hope to have the new premises open and operational by April in time for the expected 100,000 visitors coming to Cork this summer.
They said the new location is more prominent with a higher number of passing tourists.
Fáilte Ireland secured the lease for the building in 2016. It had previously been home to Blacktie menswear store.
A spokesperson for Fáilte Ireland said, "[We] believe that this move will ensure visitors receive an even greater welcome and level of service when visiting Cork. The new office, which will be Fáilte Ireland's first new design 'free flow' office to be launched, will be a major enhancement to the building fabric of the city's most iconic street."
He said the prominent building on the corner with Lavitt's Quay had become an eyesore.
The building was subsequently painted over and now fir out works will commence next week.
The work will include a new shopfront facing onto Lavitt's Quay and St Patrick's Street together with raised backlit signage.